Understanding coeliac disease
Coeliac disease is an autoimmune disorder in which the ingestion of gluten — a protein found in wheat, barley, and rye — triggers an immune response that damages the lining of the small intestine. This damage impairs nutrient absorption and can lead to a range of health problems.
Common symptoms
The symptoms of coeliac disease can vary widely, and they may manifest differently in different individuals. Common symptoms include:
- Digestive issues: Bloating, abdominal pain, diarrhoea, constipation, and nausea
- Fatigue and weakness: Persistent tiredness or low energy levels
- Unexplained weight loss: Losing weight without an obvious reason
- Skin problems: Itchy, blistering rash known as dermatitis herpetiformis
- Nutritional deficiencies: Symptoms like anaemia, vitamin deficiencies (such as iron or vitamin D), and bone pain
- Growth issues: In children, delayed growth or development.
Who might experience coeliac disease?
Coeliac disease can affect anyone, but certain groups are at higher risk:
- Family history: If you have a first-degree relative with coeliac disease, your risk is increased
- Genetic predisposition: Individuals with specific genetic markers (HLA-DQ2 or HLA-DQ8) are more likely to develop the condition
- Personal history: People with other autoimmune disorders, such as Type 1 diabetes or thyroid disease, may be more susceptible
Early detection is crucial for managing coeliac disease effectively. Without a proper diagnosis, continued gluten consumption can lead to ongoing damage to the small intestine, worsening symptoms, and potentially serious complications such as osteoporosis, infertility, or neurological problems.
By using this coeliac test, you can get immediate answers about whether you might be experiencing an immune response to gluten consistent with coeliac disease. This can help you make informed decisions about seeking further medical advice and adopting a gluten-free diet, which is the primary treatment for coeliac disease.
Key information
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Detects IgA antibodies to human tTG in human whole blood, serum, or plasma as an aid in the diagnosis of coeliac disease
- Easy-to-follow instructions
- Results in 10 minutes
- Test in the comfort of your own home
What does this coeliac test detect?
This coeliac test is designed to detect IgA antibodies against tissue transglutaminase (tTG) in human whole blood, serum, or plasma. These antibodies are commonly associated with coeliac disease, an autoimmune condition triggered by gluten consumption.
The test uses a rapid chromatographic immunoassay to provide qualitative results, indicating whether these specific antibodies are present. By identifying the presence of IgA antibodies, the test aids in the diagnosis of coeliac disease, helping you determine whether further medical evaluation is needed.
The compact kit includes all necessary components and clear instructions, making it easy to perform the test and interpret the results within just 10 minutes.
Is this the same as a gluten intolerance test?
Coeliac disease and general gluten intolerance (also called non-coeliac gluten sensitivity) are different conditions. This test looks for tTG antibodies specific to coeliac disease — an autoimmune reaction to gluten. Non-coeliac gluten sensitivity doesn't involve these antibodies and currently has no reliable blood test; it's usually identified by symptom response to removing and reintroducing gluten under medical guidance. If your antibody result is negative but you still react to gluten, that points toward gluten sensitivity rather than coeliac disease, and is worth discussing with your doctor.
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