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1. Histidyl-tRNA Synthetase (Jo-1)
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2. PM-Scl 100
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3. Centromere Protein B
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4. Scl-70
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5. Ro/SS-A (60kDa)
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6. Ro/SS-A (52kDa)
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7. La/SS-B
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8. M2 (Mitochondrial Antibody)
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9. dsDNA
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10. Nucleosome
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11. Histone
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12. Proliferating Cell Nuclear Antigen (PCNA)
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13. Ribosomal Phosphoprotein P0
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14. Sm (Smith Antigen)
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15. U1-snRNP 68/70 kDa
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16. U1-snRNP A
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17. U1-snRNP C
-
18. RNP/Sm
What is an Autoimmune & Immune Response Test?
An ANA (antinuclear antibody) test is a widely used clinical tool that helps assess whether the immune system may be reacting against the body’s own cells. It is commonly used as an initial investigation when autoimmune conditions are suspected.
However, autoimmune conditions can be complex and difficult to identify. Symptoms such as fatigue, joint discomfort and inflammation often overlap with other health concerns, and immune activity can involve multiple pathways beyond those assessed by ANA alone.
That’s why this panel goes beyond traditional ANA-only screening, analysing 18 clinically relevant markers to provide a broader overview of immune system activity across:
✔ Systemic immune activity
✔ Connective tissue markers
✔ Muscle & joint-related markers
✔ Gland & organ-related responses
By combining multiple markers into a single panel, this test is designed to provide wider insight into autoimmune-related immune activity and more structured result categorisation.
Who is this test for?
If you’ve been experiencing ongoing symptoms with no clear answers, this test helps uncover whether your immune system may be reacting abnormally so you can take the next step with confidence.
You may benefit if you experience:
Ongoing fatigue or low energy
Joint pain, stiffness, or discomfort
Brain fog or difficulty concentrating
Inflammation or swelling
Skin flare-ups or ongoing skin irritation
Muscle aches or weakness
Digestive discomfort
Feeling constantly run down with no clear reason?
A clinically recognised test, made more accessible
ANA testing is commonly used within the NHS as a first step in investigating autoimmune conditions such as lupus. Autoimmune conditions can be complex and often require multiple tests to help understand underlying immune system activity.
UK clinical guidelines support the use of autoantibody testing when autoimmune conditions are suspected.
Autoantibody panels are widely used in rheumatology to assess conditions affecting joints, connective tissues, and the immune system.
This test is not intended to diagnose medical conditions but provides insights that may support further investigation with a qualified healthcare professional.
What’s tested
Most ANA tests check 1 or 2 markers. Ours checks 18.
Frequently asked questions
Answering your questions on the Autoimmune & Immune Response TestAn ANA (antinuclear antibody) test measures antibodies that may indicate your immune system is reacting against your own body. It is commonly used in clinical settings to help investigate autoimmune conditions.
Autoimmune tests analyse specific antibodies in your blood that may be linked to immune system activity affecting joints, muscles, skin, glands, and internal organs.
Yes. ANA testing is commonly used within the NHS as part of the investigation process when autoimmune conditions such as lupus are suspected.
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